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Prime Minister Justin Trudeau called the plane crash in Tehran that killed 176 people "heartbreaking." One newspaper reported that nearly half of the Canadians who died are from the Edmonton area.

NPR speaks with Seyed Mohammad Marandi, a professor at Tehran University in Iran, who says that if the U.S. continues its attacks, Iran will have "no option but to respond to offensive measures."

Iran strikes back. Now what? We have the latest regional analysis, from top military and diplomatic voices.

More than a dozen ballistic missiles targeted two military bases in Iraq that house U.S. and coalition forces. The attack comes less than a week after a U.S. drone strike killed an Iranian commander.

NPR's David Greene talks to Brett McGurk, ex-U.S. special envoy for countering ISIS, about the importance of the U.S. remaining in Iraq. He says if the U.S. leaves, there will be serious consequences.

NPR's Rachel Martin talks to Democratic presidential candidate Sen. Bernie Sanders about President Trump's actions on Iran and the escalation of tensions, along with the upcoming Iowa Caucuses.

Also in his tweet, Trump says he will have more to say after Iran launched missiles against U.S. military forces in Iraq. The barrage follows the U.S. killing of Iran's top general.

Iran retaliates for the killing of a top commander by launching missiles at bases in Iraq that house U.S. troops. And, a Ukrainian jetliner crashed shortly after takeoff from Tehran's airport.

Iran retaliates for the killing of a top commander by launching missiles at bases in Iraq that house U.S. troops. And, a Ukrainian jetliner crashed shortly after takeoff from Tehran's airport.

Iran launched ballistic missiles against U.S. military and coalition forces in Iraq, targeting at least two military bases. Last week Iran's top general was killed in a U.S. drone strike.