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Portman will participate in a Phase 3 clinical trial for the coronavirus vaccine. He's the first senator to participate in a trial and hopes it will promote safety of vaccines once approved.

Among the staffers named: Louisiana Rep. Cedric Richmond will lead Biden's Office of Public Engagement, and Jen O'Malley Dillon, his campaign manager, will become deputy chief of staff.

Iota diminished to a Category 1 hurricane within hours of its landfall in Nicaragua. Still, as the second strong storm to hit the region in as many weeks, Iota bears grave dangers for residents.

Shoppers kept buying electronics and home improvement supplies, but sales overall rose only 0.3% in October.

NPR's Rachel Martin talks to Dr. Anthony Fauci, the country's top infectious disease expert, about promising results for vaccine candidates and his advice for staying safe during the holidays.

President Trump lost, but House Republicans had a better-than-anticipated 2020 election. They picked up at least eight seats and narrowed the House Democrats' majority.

NPR's Steve Inskeep talks toWashington Post reporter Amy Gardner about her interview with Georgia's secretary of state who says fellow Republicans are pressuring him to find ways to exclude ballots.

President-elect Joe Biden could be the first Democrat since 1885 to enter office without his party controlling both houses of Congress. That creates challenges for his ambitious agenda.

California Gov. Gavin Newsom says he is "pulling an emergency brake" to roll back business reopenings. The state has seen a major surge in new coronavirus cases in recent days.

As COVID-19 cases rise, states order restrictive measures. Why temperature matters for leading vaccines. Plus, Trump is expected to order major troop withdrawals from Afghanistan, Iraq and Somalia.